HOXA10 and POLR3D

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXA10	POLR3D
Description		homeobox A10	RNA polymerase III subunit D
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Histone Deacetylase Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Uterus Development	Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs		Calcitriol
Diseases
GWAS		Dental caries ( 23259602) Hypertension ( 31879980 30487518) Mean arterial pressure ( 30487518) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Hypertriglyceridemia ( 23505323)
Interacting Genes		16 interacting genes: CREBBP EMX1 EP300 FOXO1 GMNN GNG13 HMGB1 MAD1L1 MEIS1 NAB2 PBX1 POLR3D PTPN6 SIRT2 SNAPC1 SPI1	14 interacting genes: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 OGT POLR3E RBFOX2 RHOXF2 TAB1 ZNF496
Entrez ID		3206	661
HPRD ID		00845	01755
Ensembl ID		ENSG00000253293	ENSG00000168495
Uniprot IDs		P31260	P05423
PDB IDs			7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59
Enriched GO Terms of Interacting Partners?
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