POLR3D and NR2E3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		POLR3D	NR2E3
Description		RNA polymerase III subunit D	nuclear receptor subfamily 2 group E member 3
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GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cell Differentiation Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Retina Development In Camera-type Eye
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Red blood cell count ( 32888494)
Interacting Genes		14 interacting genes: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 OGT POLR3E RBFOX2 RHOXF2 TAB1 ZNF496	29 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 WDR5 ZNF232
Entrez ID		661	10002
HPRD ID		01755	05132
Ensembl ID		ENSG00000168495	ENSG00000278570
Uniprot IDs		P05423	F1D8Q9 Q9Y5X4
PDB IDs		7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59	4LOG
Enriched GO Terms of Interacting Partners?
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