C14orf39 and HPGDS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C14orf39	HPGDS
Description		chromosome 14 open reading frame 39	hematopoietic prostaglandin D synthase
Image		No pdb structure
GO Annotations	Cellular Component	Central Element Cellular_component Chromosome	Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	Magnesium Ion Binding Glutathione Transferase Activity Prostaglandin-D Synthase Activity Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination Oogenesis Regulation Of DNA-binding Transcription Factor Activity	Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Locomotory Behavior
Pathways			Glutathione conjugation Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs			Glutathione Tretinoin 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride Glutathione disulfide 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE Tranilast 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE Nocodazole 3-(4-nitrophenyl)-1H-pyrazole 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Diseases
GWAS		Body shape index ( 34021172) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549) Height ( 28552196 25282103 23563607) Hip circumference adjusted for BMI ( 28552196 34021172) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576 29875488) Testicular germ cell tumor ( 28604728 28604732 23666239)
Interacting Genes		5 interacting genes: HPGDS MT1X PRKCH TEAD2 TRIM54	7 interacting genes: ABHD17A ARRDC3 C14orf39 HK3 LIF MELTF PDE3B
Entrez ID		317761	27306
HPRD ID		08504	04001
Ensembl ID		ENSG00000179008	ENSG00000163106
Uniprot IDs		Q8N1H7	A0A384P5J0 O60760
PDB IDs			1IYH 1IYI 1V40 2CVD 2VCQ 2VCW 2VCX 2VCZ 2VD0 2VD1 3EE2 3KXO 3VI5 3VI7 4EC0 4EDY 4EDZ 4EE0 5AIS 5AIV 5AIX 5YWE 5YWX 5YX1 6N4E 6W58 6W8H
Enriched GO Terms of Interacting Partners?
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