HPGDS and C14orf39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HPGDS	C14orf39
Description		hematopoietic prostaglandin D synthase	chromosome 14 open reading frame 39
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Central Element Cellular_component Chromosome
	Molecular Function	Magnesium Ion Binding Glutathione Transferase Activity Prostaglandin-D Synthase Activity Calcium Ion Binding Protein Binding Protein Homodimerization Activity	Molecular_function Protein Binding
	Biological Process	Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Locomotory Behavior	Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination Oogenesis Regulation Of DNA-binding Transcription Factor Activity
Pathways		Glutathione conjugation Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Glutathione Tretinoin 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride Glutathione disulfide 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE Tranilast 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE Nocodazole 3-(4-nitrophenyl)-1H-pyrazole 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576 29875488) Testicular germ cell tumor ( 28604728 28604732 23666239)	Body shape index ( 34021172) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549) Height ( 28552196 25282103 23563607) Hip circumference adjusted for BMI ( 28552196 34021172) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		7 interacting genes: ABHD17A ARRDC3 C14orf39 HK3 LIF MELTF PDE3B	5 interacting genes: HPGDS MT1X PRKCH TEAD2 TRIM54
Entrez ID		27306	317761
HPRD ID		04001	08504
Ensembl ID		ENSG00000163106	ENSG00000179008
Uniprot IDs		A0A384P5J0 O60760	Q8N1H7
PDB IDs		1IYH 1IYI 1V40 2CVD 2VCQ 2VCW 2VCX 2VCZ 2VD0 2VD1 3EE2 3KXO 3VI5 3VI7 4EC0 4EDY 4EDZ 4EE0 5AIS 5AIV 5AIX 5YWE 5YWX 5YX1 6N4E 6W58 6W8H
Enriched GO Terms of Interacting Partners?
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