HPGDS

Description		hematopoietic prostaglandin D synthase
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding Glutathione Transferase Activity Prostaglandin-D Synthase Activity Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Locomotory Behavior
Pathways		Glutathione conjugation Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Glutathione Tretinoin 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride Glutathione disulfide 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE Tranilast 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE Nocodazole 3-(4-nitrophenyl)-1H-pyrazole 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576 29875488) Testicular germ cell tumor ( 28604728 28604732 23666239)
Interacting Genes		7 interacting genes: ABHD17A ARRDC3 C14orf39 HK3 LIF MELTF PDE3B
Entrez ID		27306
HPRD ID		04001
Ensembl ID		ENSG00000163106
Uniprot IDs		A0A384P5J0 O60760
PDB IDs		1IYH 1IYI 1V40 2CVD 2VCQ 2VCW 2VCX 2VCZ 2VD0 2VD1 3EE2 3KXO 3VI5 3VI7 4EC0 4EDY 4EDZ 4EE0 5AIS 5AIV 5AIX 5YWE 5YWX 5YX1 6N4E 6W58 6W8H
Enriched GO Terms of Interacting Partners?
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