C14orf39 and PRKCH

		C14orf39	PRKCH
Description		chromosome 14 open reading frame 39	protein kinase C eta
Image		No pdb structure
GO Annotations	Cellular Component	Central Element Cellular_component Chromosome	Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Enzyme Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination Oogenesis Regulation Of DNA-binding Transcription Factor Activity	Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly
Pathways			Effects of PIP2 hydrolysis G alpha (z) signalling events
Drugs
Diseases
GWAS		Body shape index ( 34021172) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549) Height ( 28552196 25282103 23563607) Hip circumference adjusted for BMI ( 28552196 34021172) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 30423114 22446963 24390342) Word reading ( 23738518) Yeast infection ( 28928442)
Interacting Genes		5 interacting genes: HPGDS MT1X PRKCH TEAD2 TRIM54	17 interacting genes: BANP BMP4 C14orf39 CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SIX6 SRC ZBTB8OS ZFP36L1 ZFYVE1
Entrez ID		317761	5583
HPRD ID		08504	05669
Ensembl ID		ENSG00000179008	ENSG00000027075
Uniprot IDs		Q8N1H7	P24723
PDB IDs			2FK9 3TXO
Enriched GO Terms of Interacting Partners?
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