SLC29A2 and LAPTM4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC29A2	LAPTM4B
Description		solute carrier family 29 member 2	lysosomal protein transmembrane 4 beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Nuclear Membrane Presynapse	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle
	Molecular Function	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Neurotransmitter Uptake Neurotransmitter Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Adenosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways		Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs		Ethanol
Diseases
GWAS		Bipolar disorder ( 21926972) Serum metabolite levels ( 33031748) Serum uric acid levels ( 32514006)	Metabolite levels ( 23823483) QT interval ( 24952745)
Interacting Genes		19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2	22 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM67 TMEM86B TRARG1
Entrez ID		3177	55353
HPRD ID		03662	13960
Ensembl ID		ENSG00000174669	ENSG00000104341
Uniprot IDs		G5E943 Q14542 Q96FB2	Q86VI4
PDB IDs
Enriched GO Terms of Interacting Partners?
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