HLA-DPA1 and CD74

  • Number of citations of the paper that reports this interaction (PubMedID 16242130)
  • 7
  • Data Source:
  • HPRD (in vivo)

HLA-DPA1

CD74

Description major histocompatibility complex, class II, DP alpha 1 CD74 molecule
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757)
  • Asthma ( 30929738 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Chronic hepatitis B infection ( 25802187)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Hepatitis B ( 21750111)
  • Hepatitis B (viral clearance) ( 22737229)
  • Hip circumference adjusted for BMI ( 34021172)
  • IgA nephropathy ( 25305756)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lymphocyte percentage of white cells ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Mortality in sepsis ( 27639821)
  • Myositis ( 26291516)
  • Nephropathy ( 21399633)
  • Persistent hepatitis B virus infection ( 33736632)
  • Pulmonary arterial hypertension ( 30527956)
  • Response to hepatitis B vaccine ( 29534301)
  • Sjögren's syndrome ( 24097066)
  • Systemic lupus erythematosus ( 32771030)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes 6 interacting genes: CD4 CD74 CNMD HLA-DPB1 TMEM50A TMEM50B 44 interacting genes: APP BET1 C14orf180 CCR1 CD1D CD44 CLDN19 CLEC7A CMTM7 CTSF CTSL EDDM3B ERG28 FDFT1 FXYD6 HADHA HLA-DMA HLA-DMB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQB1 HLA-DRA LAMTOR5 LPAR3 MAP3K1 MIF PGA4 PLP1 PLPP4 POMGNT1 PTCH1 RTP2 SEC22A SERP1 SLC35B1 SMIM1 TEX11 TMEM120B TMEM243 TMEM254 TMEM60 TMEM97 UPK2
Entrez ID 3113 972
HPRD ID 00835 00825
Ensembl ID ENSG00000231389 ENSG00000019582
Uniprot IDs P20036 X5CKE2 P04233
PDB IDs 3LQZ 4P4K 4P4R 4P57 4P5K 4P5M 1A6A 1ICF 1IIE 1L3H 1MUJ 3PDO 3PGC 3PGD 3QXA 3QXD 4AEN 4AH2 4X5W 5KSU 5KSV
Enriched GO Terms of Interacting Partners?
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