HLA-DPA1 and HLA-DPB1

  • Number of citations of the paper that reports this interaction (PubMedID 26186194)
  • 524
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo)

HLA-DPA1

HLA-DPB1

Description major histocompatibility complex, class II, DP alpha 1 major histocompatibility complex, class II, DP beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757)
  • Asthma ( 30929738 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Chronic hepatitis B infection ( 25802187)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Hepatitis B ( 21750111)
  • Hepatitis B (viral clearance) ( 22737229)
  • Hip circumference adjusted for BMI ( 34021172)
  • IgA nephropathy ( 25305756)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lymphocyte percentage of white cells ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Mortality in sepsis ( 27639821)
  • Myositis ( 26291516)
  • Nephropathy ( 21399633)
  • Persistent hepatitis B virus infection ( 33736632)
  • Pulmonary arterial hypertension ( 30527956)
  • Response to hepatitis B vaccine ( 29534301)
  • Sjögren's syndrome ( 24097066)
  • Systemic lupus erythematosus ( 32771030)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes 6 interacting genes: CD4 CD74 CNMD HLA-DPB1 TMEM50A TMEM50B 9 interacting genes: CD74 COPB1 HLA-DPA1 HLA-DQA1 LZTS2 MEOX2 ROBO2 RTN4 TRIP6
Entrez ID 3113 3115
HPRD ID 00835 00832
Ensembl ID ENSG00000231389 ENSG00000223865
Uniprot IDs P20036 X5CKE2 I4EC15 P04440
PDB IDs 3LQZ 4P4K 4P4R 4P57 4P5K 4P5M 3LQZ 4P4K 4P4R 4P57 4P5K 4P5M
Enriched GO Terms of Interacting Partners?
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