GPM6A and PAM16

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		GPM6A	PAM16
Description		glycoprotein M6A	presequence translocase associated motor 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Filopodium Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Extracellular Exosome Glutamatergic Synapse Integral Component Of Presynaptic Active Zone Membrane Extracellular Vesicle	PAM Complex, Tim23 Associated Import Motor TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex
	Molecular Function	Calcium Channel Activity Protein Binding	Protein Binding
	Biological Process	Neuron Migration Neural Retina Development Synapse Assembly Response To Bacterium Neuron Projection Development Neuron Projection Morphogenesis Stem Cell Differentiation Regulation Of Synapse Organization Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport	Ossification Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Apoptotic DNA Fragmentation
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Educational attainment ( 23722424) Household income (MTAG) ( 31844048) Major depressive disorder x sex interaction ( 34099189) Mortality in heart failure ( 20400778) Schizophrenia ( 28991256 25056061 29483656 30285260) Sensorimotor dexterity ( 31596458) Sepsis (28-day mortality) ( 32592749) Temperament (bipolar disorder) ( 22365631)	Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: CASP3 CEP44 FBXO8 GABARAPL2 PAM16 PRKCA	9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1
Entrez ID		2823	51025
HPRD ID		03174	14798
Ensembl ID		ENSG00000150625	ENSG00000217930
Uniprot IDs		P51674	Q9Y3D7
PDB IDs
Enriched GO Terms of Interacting Partners?
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