GPM6A and FBXO8

		GPM6A	FBXO8
Description		glycoprotein M6A	F-box protein 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Filopodium Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Extracellular Exosome Glutamatergic Synapse Integral Component Of Presynaptic Active Zone Membrane Extracellular Vesicle	Ubiquitin Ligase Complex
	Molecular Function	Calcium Channel Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Neuron Migration Neural Retina Development Synapse Assembly Response To Bacterium Neuron Projection Development Neuron Projection Morphogenesis Stem Cell Differentiation Regulation Of Synapse Organization Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Educational attainment ( 23722424) Household income (MTAG) ( 31844048) Major depressive disorder x sex interaction ( 34099189) Mortality in heart failure ( 20400778) Schizophrenia ( 28991256 25056061 29483656 30285260) Sensorimotor dexterity ( 31596458) Sepsis (28-day mortality) ( 32592749) Temperament (bipolar disorder) ( 22365631)	Chin dimples ( 27182965) Copper levels ( 26025379) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		6 interacting genes: CASP3 CEP44 FBXO8 GABARAPL2 PAM16 PRKCA	7 interacting genes: CDK4 GPM6A HIF1A MTOR MYC SKP1 TRIP13
Entrez ID		2823	26269
HPRD ID		03174	07293
Ensembl ID		ENSG00000150625	ENSG00000164117
Uniprot IDs		P51674	A0A0S2Z5D1 Q8IXA8 Q9NRD0
PDB IDs
Enriched GO Terms of Interacting Partners?
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