FBXO8 and GPM6A

		FBXO8	GPM6A
Description		F-box protein 8	glycoprotein M6A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex	Plasma Membrane Filopodium Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Extracellular Exosome Glutamatergic Synapse Integral Component Of Presynaptic Active Zone Membrane Extracellular Vesicle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	Calcium Channel Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	Neuron Migration Neural Retina Development Synapse Assembly Response To Bacterium Neuron Projection Development Neuron Projection Morphogenesis Stem Cell Differentiation Regulation Of Synapse Organization Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Copper levels ( 26025379) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Educational attainment ( 23722424) Household income (MTAG) ( 31844048) Major depressive disorder x sex interaction ( 34099189) Mortality in heart failure ( 20400778) Schizophrenia ( 28991256 25056061 29483656 30285260) Sensorimotor dexterity ( 31596458) Sepsis (28-day mortality) ( 32592749) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		7 interacting genes: CDK4 GPM6A HIF1A MTOR MYC SKP1 TRIP13	6 interacting genes: CASP3 CEP44 FBXO8 GABARAPL2 PAM16 PRKCA
Entrez ID		26269	2823
HPRD ID		07293	03174
Ensembl ID		ENSG00000164117	ENSG00000150625
Uniprot IDs		A0A0S2Z5D1 Q8IXA8 Q9NRD0	P51674
PDB IDs
Enriched GO Terms of Interacting Partners?
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