DESI1 and ABI3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DESI1	ABI3
Description		desumoylating isopeptidase 1	ABI family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Intracellular Anatomical Structure Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity	Protein Binding SH3 Domain Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal	Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CENPM CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RBX1 RNF4 RPS27A SHISA4 SHISA5 SLC25A17 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		27351	51225
HPRD ID		18590	05900
Ensembl ID		ENSG00000100418	ENSG00000108798
Uniprot IDs		Q6ICB0	Q9P2A4
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?
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