ABI3 and KRT35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ABI3	KRT35
Description		ABI family member 3	keratin 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft	Extracellular Space Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding Identical Protein Binding Actin Filament Binding	Structural Molecule Activity Protein Binding
	Biological Process	Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Cellular Senescence	Anatomical Structure Morphogenesis
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1	87 interacting genes: ABI3 ATG9A BCAS2 C1orf109 C21orf58 CCDC120 CCDC185 CCDC196 CCHCR1 CD33 CTSZ DMRT3 DTNB EFCAB3 ENKD1 EXOSC5 FAM221B FRS3 HAPLN2 HCK HDAC4 HGS HOXA1 HOXC8 KCTD9 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 LONRF1 MAPKBP1 MCRS1 MYO15B OIP5 OTX1 PKN1 POU4F2 PRPF18 PRPF31 PRR35 RUNX1T1 SCNM1 SHC3 SLC43A2 SMARCE1 SMYD1 TAPBPL TBC1D21 TBC1D30 TBC1D7 TCEANC TCHP TEKT4 TEPSIN TLE5 TRIM29 TSG101 TXLNA TXLNB UBASH3A USP2 VPS9D1 ZNF417 ZNF446
Entrez ID		51225	3886
HPRD ID		05900	04138
Ensembl ID		ENSG00000108798	ENSG00000197079
Uniprot IDs		Q9P2A4	Q92764
PDB IDs
Enriched GO Terms of Interacting Partners?
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