DESI1 and PRR5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DESI1	PRR5
Description		desumoylating isopeptidase 1	proline rich 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Cytosol TORC2 Complex
	Molecular Function	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity	Protein Binding
	Biological Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal	Positive Regulation Of Protein Phosphorylation Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling TORC2 Signaling
Pathways			PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)
Interacting Genes		35 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CENPM CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RBX1 RNF4 RPS27A SHISA4 SHISA5 SLC25A17 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	8 interacting genes: CTNNA3 DESI1 GPSM3 HGS SCUBE1 TTC38 USHBP1 WNT7B
Entrez ID		27351	55615
HPRD ID		18590	18696
Ensembl ID		ENSG00000100418	ENSG00000186654
Uniprot IDs		Q6ICB0	A0A024R4U5 A8K699 P85299
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?
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