Description |
DISC1 scaffold protein |
dynactin subunit 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alzheimer's disease ( 19118814)
- Amyotrophic lateral sclerosis ( 19451621)
- Amyotrophic lateral sclerosis (sporadic) ( 24529757)
- Arterial stiffness index ( 31235810)
- Bell's palsy ( 33602968)
- Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451)
- Metabolite levels ( 23823483)
- Neuranatomic and neurocognitive phenotypes ( 21483430)
- Pelvic organ prolapse (moderate/severe) ( 26545240)
- Response to antidepressants (symptom improvement) ( 29160301)
- Response to antineoplastic agents ( 21659360)
- Response to statin therapy ( 20339536)
- Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592)
- Waist circumference ( 28552196)
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- Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
- Refractive error ( 32231278)
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Interacting Genes |
194 interacting genes:
ABI2
ACTG1
ACTN2
ADO
AGTPBP1
AIMP2
AKAP6
ALDH3A2
AMOT
AP1M1
ARIH2
ARMC7
ATF4
ATF5
ATF7IP
BAG2
BFSP2
BICD1
BORCS6
BRD1
C1orf109
C2CD6
C8orf33
CARD9
CCDC102B
CCDC13
CCDC136
CCDC141
CCDC197
CCDC24
CCDC57
CCDC88A
CCDC92
CCHCR1
CDC23
CDC37
CDC5L
CDK5RAP3
CDKL3
CEP126
CEP57
CEP57L1
CEP63
CFAP206
CIT
CLU
CNST
COL4A1
CTNNA3
CWF19L2
DCTN1
DCTN2
DDX6
DEGS1
DMD
DNAJC7
DPYSL2
DPYSL3
DST
DYNC1H1
EEF2
EGLN1
EIF3H
EIF4A3
EMSY
EXOC1
EXOC4
EXOC7
EXTL1
FBXO34
FBXO41
FBXW7
FEZ1
FLACC1
FRYL
GABARAPL1
GAS2L2
GAS8
GCC1
GEM
GNB1
GNG13
GNPTAB
GPANK1
GPRASP2
GRIPAP1
GSK3B
HERC2P2
HNRNPC
IFT20
IFT74
IMMT
ITSN1
KALRN
KANSL1
KCNQ5
KIF3A
KIF3C
KIF9
KIFAP3
KIFC3
LENG1
MACF1
MAP1A
MEMO1
MLLT10
MNS1
MORF4L2
MPPED1
MVP
MYH7
MYT1L
NCK2
NDE1
NDEL1
NECAB1
NEFM
NME7
NSRP1
NUP160
OLFM1
PCNT
PCNX4
PDE4B
PGK1
PHF1
PIBF1
PIK3R3
PKN1
POLR3C
PPFIA3
PPM1E
PPP4R1
PPP5C
PSPC1
QARS1
RABGAP1
RAD21
RANBP9
RASSF7
RBM41
RBSN
RECK
RNF40
ROGDI
RTRAF
SH3BP5
SMARCD1
SMARCE1
SMC2
SMC3
SMC5
SMYD1
SNX6
SPARCL1
SPATC1L
SPTBN4
SRGAP2
SRGAP3
STX11
STX18
SUFU
SYBU
SYNE1
TCAF1
TCEANC
TFIP11
TIAM2
TNKS
TP53BP2
TRAF3IP1
TRAF4
TRIM29
TRIM68
TRIO
TSGA10
TSPOAP1
TSR2
TTC23
TUBB
TUBB2A
UBASH3A
UBASH3B
USP2
UTRN
XPNPEP1
YWHAE
YWHAG
YWHAQ
YWHAZ
ZNF124
ZNF197
ZNF365
ZNF76
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51 interacting genes:
ACTR1A
ACTR1B
AKT1
APEX1
BBS1
BBS4
BICD1
BICD2
CASP2
CASP3
CASP7
CDC37
CLIP1
DCTN3
DISC1
DST
DTNBP1
DYNC1I2
ENO3
FBXL5
FXR1
GRB2
GSK3B
HAP1
HOXA1
HSPB2
KIAA0408
KIF11
KMT2A
KRT5
MAP2K3
MAP2K6
MAPRE1
MED14
MTERF1
NEK2
NOD2
PAFAH1B1
PFDN1
PGAM1
PPP1CA
RAB6A
RBL2
RPGR
SEC23A
SPTBN2
STAT1
TMED5
TP53RK
VIM
ZNF512B
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Entrez ID |
27185 |
1639 |
HPRD ID |
05553 |
07206 |
Ensembl ID |
ENSG00000162946
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ENSG00000204843
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Uniprot IDs |
C4P094
C4P096
C4P098
C4P0A4
C4P0A5
C4P0C4
C4P0C8
C4P0D0
C4P0D1
C4P0D2
C4P0D3
Q9NRI5
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Q14203
Q6MZZ3
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PDB IDs |
5V4B
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1TXQ
2COY
2HKN
2HKQ
2HL3
2HL5
2HQH
3E2U
3TQ7
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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