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POLD2
Description
DNA polymerase delta 2, accessory subunit
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Zeta DNA Polymerase Complex
DNA Polymerase Complex
Delta DNA Polymerase Complex
Molecular Function
DNA Binding
Protein Binding
Biological Process
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
DNA Biosynthetic Process
Pathways
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand
Drugs
Diseases
GWAS
Interacting Genes
19 interacting genes:
CCHCR1
CDK2
CDKN1A
EP300
ERBB2
KCTD13
LSM6
OGT
PCNA
POLD1
POLD3
POLD4
POLDIP2
POLDIP3
POLH
SOX12
WRN
WRNIP1
XRN1
Entrez ID
5425
HPRD ID
15982
Ensembl ID
ENSG00000106628
Uniprot IDs
A0A087WWF6
P49005
PDB IDs
3E0J
6S1M
6S1N
6S1O
6TNY
6TNZ
Enriched GO Terms of Interacting Partners
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