ACSL6 and ARHGAP26

		ACSL6	ARHGAP26
Description		acyl-CoA synthetase long chain family member 6	Rho GTPase activating protein 26
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cellular_component Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Protein Homodimerization Activity Arachidonate-CoA Ligase Activity	GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Lipid Biosynthetic Process Long-chain Fatty-acyl-CoA Biosynthetic Process	Signal Transduction Nervous System Development Actin Cytoskeleton Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Synthesis of very long-chain fatty acyl-CoAs	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908 23128233) Perceived unattractiveness to mosquitoes ( 28199695) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) LDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Pulse pressure ( 27841878) Septic shock resolution ( 32755526) Suicide attempt severity in mood disorders ( 33783297) Waist circumference ( 28552196)
Interacting Genes		12 interacting genes: ARHGAP26 GATM HGD KLHL3 NRSN1 PCDHB5 PCMTD2 PHYH POLR2L SEPTIN8 TCERG1 ZNF655	9 interacting genes: ACSL6 CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1
Entrez ID		23305	23092
HPRD ID		09190	05643
Ensembl ID		ENSG00000164398	ENSG00000145819
Uniprot IDs		B2RB13 B4DFW3 Q9UKU0	A0A0S2Z536 Q9UNA1
PDB IDs			1UGV
Enriched GO Terms of Interacting Partners?
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