ACSL6 and HGD

		ACSL6	HGD
Description		acyl-CoA synthetase long chain family member 6	homogentisate 1,2-dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Protein Homodimerization Activity Arachidonate-CoA Ligase Activity	Homogentisate 1,2-dioxygenase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Lipid Biosynthetic Process Long-chain Fatty-acyl-CoA Biosynthetic Process	L-phenylalanine Catabolic Process Tyrosine Catabolic Process
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Tyrosine catabolism
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908 23128233) Perceived unattractiveness to mosquitoes ( 28199695) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		12 interacting genes: ARHGAP26 GATM HGD KLHL3 NRSN1 PCDHB5 PCMTD2 PHYH POLR2L SEPTIN8 TCERG1 ZNF655	6 interacting genes: ACSL6 CLDN7 GIT2 NTAQ1 PCDHGC3 TERF1
Entrez ID		23305	3081
HPRD ID		09190	06315
Ensembl ID		ENSG00000164398	ENSG00000113924
Uniprot IDs		B2RB13 B4DFW3 Q9UKU0	B3KW64 Q93099
PDB IDs			1EY2 1EYB
Enriched GO Terms of Interacting Partners?
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