NYAP1 and NCKAP1

Number of citations of the paper that reports this interaction (PubMedID 21946561)
21

Data Source:
BioGRID (pull down)

		NYAP1	NCKAP1
Description		neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1	NCK associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Ruffle Cytosol Focal Adhesion Integral Component Of Membrane Lamellipodium SCAR Complex Lamellipodium Membrane Filamentous Actin Extracellular Exosome
	Molecular Function		Protein Binding Small GTPase Binding
	Biological Process	Phosphatidylinositol 3-kinase Signaling Neuron Projection Morphogenesis	Cell Morphogenesis Apoptotic Process Central Nervous System Development Positive Regulation Of Lamellipodium Assembly Cell Migration Rac Protein Signal Transduction Cell Projection Assembly Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		3 interacting genes: CYFIP1 NCKAP1 PIK3R1	14 interacting genes: ABI1 BRK1 CYFIP2 DNMBP GAS7 MYO16 NCK1 NYAP1 NYAP2 RAC1 SPP1 WASF1 WASF2 YWHAG
Entrez ID		222950	10787
HPRD ID		13427	05353
Ensembl ID		ENSG00000166924	ENSG00000061676
Uniprot IDs		Q6ZVC0	Q9Y2A7
PDB IDs			3P8C 4N78
Enriched GO Terms of Interacting Partners?
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