NCKAP1 and DNMBP

Number of citations of the paper that reports this interaction (PubMedID 14506234)
68

Data Source:
HPRD (in vitro)

		NCKAP1	DNMBP
Description		NCK associated protein 1	dynamin binding protein
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GO Annotations	Cellular Component	Ruffle Cytosol Focal Adhesion Integral Component Of Membrane Lamellipodium SCAR Complex Lamellipodium Membrane Filamentous Actin Extracellular Exosome	Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Synapse Presynapse
	Molecular Function	Protein Binding Small GTPase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cell Morphogenesis Apoptotic Process Central Nervous System Development Positive Regulation Of Lamellipodium Assembly Cell Migration Rac Protein Signal Transduction Cell Projection Assembly Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	CDC42 GTPase cycle
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		14 interacting genes: ABI1 BRK1 CYFIP2 DNMBP GAS7 MYO16 NCK1 NYAP1 NYAP2 RAC1 SPP1 WASF1 WASF2 YWHAG	20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		10787	23268
HPRD ID		05353	10918
Ensembl ID		ENSG00000061676	ENSG00000107554
Uniprot IDs		Q9Y2A7	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs		3P8C 4N78	1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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