NCKAP1 and NYAP1

Number of citations of the paper that reports this interaction (PubMedID 21946561)
21

Data Source:
BioGRID (pull down)

		NCKAP1	NYAP1
Description		NCK associated protein 1	neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Focal Adhesion Integral Component Of Membrane Lamellipodium SCAR Complex Lamellipodium Membrane Filamentous Actin Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding
	Biological Process	Cell Morphogenesis Apoptotic Process Central Nervous System Development Positive Regulation Of Lamellipodium Assembly Cell Migration Rac Protein Signal Transduction Cell Projection Assembly Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Phosphatidylinositol 3-kinase Signaling Neuron Projection Morphogenesis
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639)	Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: ABI1 BRK1 CYFIP2 DNMBP GAS7 MYO16 NCK1 NYAP1 NYAP2 RAC1 SPP1 WASF1 WASF2 YWHAG	3 interacting genes: CYFIP1 NCKAP1 PIK3R1
Entrez ID		10787	222950
HPRD ID		05353	13427
Ensembl ID		ENSG00000061676	ENSG00000166924
Uniprot IDs		Q9Y2A7	Q6ZVC0
PDB IDs		3P8C 4N78
Enriched GO Terms of Interacting Partners?
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