Description |
DCC netrin 1 receptor |
siah E3 ubiquitin protein ligase 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Age at first sexual intercourse ( 27089180 34211149)
- Alcoholism (alcohol use disorder factor score) ( 21529783)
- Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Benign prostatic hyperplasia ( 30988330)
- Body mass index ( 28892062)
- Body mass index (ever vs never smoking interaction) ( 23192594)
- Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
- Brain morphology (MOSTest) ( 32665545)
- Chronic back pain ( 30261039)
- Coenzyme Q10 levels ( 27149984)
- Cognitive ability ( 29186694)
- Cognitive ability (MTAG) ( 29186694)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Depression ( 27089181 33859377 29700475)
- Experiencing mood swings ( 29500382)
- Feeling fed-up ( 29500382)
- Feeling miserable ( 29500382)
- Gallbladder cancer ( 22318345)
- Gastroesophageal reflux disease ( 34187846)
- General cognitive ability ( 29844566)
- General factor of neuroticism ( 30867560)
- Glucose homeostasis traits ( 25524916)
- Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821)
- Homeostasis model assessment of insulin resistance ( 33381925)
- Household income (MTAG) ( 31844048)
- Intelligence (MTAG) ( 29326435)
- Intraocular pressure ( 30591961)
- Lung function (FVC) ( 30061609 30804560)
- Mood instability ( 31168069 29187730)
- Mosquito bite size ( 28199695)
- Multisite chronic pain ( 33830993 31194737)
- Neurociticism ( 29500382)
- Nickel levels ( 26025379)
- Number of sexual partners ( 30643258)
- Obesity-related traits ( 23251661)
- Putamen volume ( 29147026)
- Response to exercise (triglyceride level interaction) ( 26491034)
- Response to fenofibrate (total cholesterol levels) ( 27002377)
- Response to mTOR inhibitor (everolimus) ( 24009623)
- Risk-taking tendency (4-domain principal component model) ( 30643258)
- Schizophrenia ( 33169155 30285260)
- Short-term memory (digit-span task) ( 30741946)
- Smoking behaviour (cigarettes smoked per day) ( 27393504)
- Smoking initiation ( 33082346)
- Smoking status (ever vs never smokers) ( 30643258)
- Subcortical brain region volumes ( 25607358)
- Survival in colorectal cancer (distant metastatic) ( 26586795)
- White matter hyperintensity volume ( 33293549)
- White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
- White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
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Interacting Genes |
38 interacting genes:
ADORA2B
AFDN-DT
ALDOB
ANP32B
APPL1
AR
ARG2
BARD1
CASP3
CASP9
CORO2A
CTSV
FBP1
FECH
GPI
HEMGN
MAPK3
MAZ
NARS1
NCK1
NSDHL
NTN1
PITPNA
POLR2E
PTK2
RASA1
RPL5
SERPINB2
SFRP2
SIAH1
SIAH2
TBC1D2
TDRD7
TMOD1
TNNI1
TRMO
TSTD2
TULP4
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152 interacting genes:
AASDHPPT
AFF1
AFF4
APC
AQP1
ARMC9
ATN1
ATXN7
AXIN1
BAG1
BAG3
BAG4
BCL6
CACYBP
CAPG
CCDC198
CDC23
CDC34
CDK5R1
DAB1
DCC
DDX41
DNAJC15
DNALI1
EEF1D
EIF3J
ELL2
EXOC3-AS1
FAM90A1
FLI1
FZD9
GAPDH
GDPD5
GRM5
H4-16
HCFC1
HIF1AN
HIPK2
HIPK3
INHA
IQCN
KATNAL1
KCNJ10
KHDRBS3
KIAA0319L
KIAA1217
KIF1B
KIF22
KIFC3
KLF10
LACTB2
LANCL2
LMNA
M1AP
MAB21L1
MAP3K5
MAPK12
MAPKBP1
MAPRE3
MOB3C
MTIF3
MX1
NANOS2
NANOS3
NECTIN2
NELFA
NOL6
NTAQ1
NUMB
NUMBL
OPRM1
OTUB2
PARD6B
PEG10
PEG3
PFKM
PHC1
PHC2
PIAS2
PIAS3
PIMREG
PKD1
POU2AF1
PRPF31
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PTPMT1
PUF60
PYGB
QRICH1
RAB33A
RAB33B
RAD51AP1
RAD54L2
RAPH1
RBBP8
RICTOR
RPL27A
RPS19BP1
RXRB
SDCBP
SFMBT2
SH3RF1
SLC9A3R2
SNCAIP
SPATA4
SPATC1L
SYP
SYT7
TBC1D22B
TERF2
TFDP1
TMEM43
TNK2
TOLLIP
TP53BP2
TRIM23
TRIM27
TRIM7
TRIM8
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
TXN
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2K
UBE2L6
UBE2N
UBE2V2
UPP2
USP19
UXT
VAV1
ZBP1
ZCCHC10
ZCCHC13
ZFYVE21
ZMAT3
ZNF148
ZNF512B
ZNF671
ZYX
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Entrez ID |
1630 |
6477 |
HPRD ID |
00391 |
03736 |
Ensembl ID |
ENSG00000187323
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ENSG00000196470
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Uniprot IDs |
P43146
Q49AK4
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Q8IUQ4
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PDB IDs |
2ED7
2ED8
2ED9
2EDB
2EDD
2EDE
3AU4
4URT
5X83
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2A25
4C9Z
4CA1
4I7B
4I7C
4I7D
4X3G
5WZZ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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