Description |
DCC netrin 1 receptor |
BRCA1 associated RING domain 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Age at first sexual intercourse ( 27089180 34211149)
- Alcoholism (alcohol use disorder factor score) ( 21529783)
- Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Benign prostatic hyperplasia ( 30988330)
- Body mass index ( 28892062)
- Body mass index (ever vs never smoking interaction) ( 23192594)
- Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
- Brain morphology (MOSTest) ( 32665545)
- Chronic back pain ( 30261039)
- Coenzyme Q10 levels ( 27149984)
- Cognitive ability ( 29186694)
- Cognitive ability (MTAG) ( 29186694)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Depression ( 27089181 33859377 29700475)
- Experiencing mood swings ( 29500382)
- Feeling fed-up ( 29500382)
- Feeling miserable ( 29500382)
- Gallbladder cancer ( 22318345)
- Gastroesophageal reflux disease ( 34187846)
- General cognitive ability ( 29844566)
- General factor of neuroticism ( 30867560)
- Glucose homeostasis traits ( 25524916)
- Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821)
- Homeostasis model assessment of insulin resistance ( 33381925)
- Household income (MTAG) ( 31844048)
- Intelligence (MTAG) ( 29326435)
- Intraocular pressure ( 30591961)
- Lung function (FVC) ( 30061609 30804560)
- Mood instability ( 31168069 29187730)
- Mosquito bite size ( 28199695)
- Multisite chronic pain ( 33830993 31194737)
- Neurociticism ( 29500382)
- Nickel levels ( 26025379)
- Number of sexual partners ( 30643258)
- Obesity-related traits ( 23251661)
- Putamen volume ( 29147026)
- Response to exercise (triglyceride level interaction) ( 26491034)
- Response to fenofibrate (total cholesterol levels) ( 27002377)
- Response to mTOR inhibitor (everolimus) ( 24009623)
- Risk-taking tendency (4-domain principal component model) ( 30643258)
- Schizophrenia ( 33169155 30285260)
- Short-term memory (digit-span task) ( 30741946)
- Smoking behaviour (cigarettes smoked per day) ( 27393504)
- Smoking initiation ( 33082346)
- Smoking status (ever vs never smokers) ( 30643258)
- Subcortical brain region volumes ( 25607358)
- Survival in colorectal cancer (distant metastatic) ( 26586795)
- White matter hyperintensity volume ( 33293549)
- White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
- White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
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Interacting Genes |
38 interacting genes:
ADORA2B
AFDN-DT
ALDOB
ANP32B
APPL1
AR
ARG2
BARD1
CASP3
CASP9
CORO2A
CTSV
FBP1
FECH
GPI
HEMGN
MAPK3
MAZ
NARS1
NCK1
NSDHL
NTN1
PITPNA
POLR2E
PTK2
RASA1
RPL5
SERPINB2
SFRP2
SIAH1
SIAH2
TBC1D2
TDRD7
TMOD1
TNNI1
TRMO
TSTD2
TULP4
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129 interacting genes:
ACP1
ACSL3
AKIP1
AP1B1
ASH2L
ATP1B1
ATP1B3
AXIN2
BCCIP
BCL3
BRCA1
BRD7
CAP1
CBX1
CBX3
CBX5
CCDC136
CDK1
CDK2
CEP70
CHD3
CNTN4
COL1A1
COMMD1
CSTF1
DCC
DDX39B
DNAI7
ELP1
ESR1
EWSR1
EXOC5
FAM9B
FEZ1
FKBP1A
FKBP2
FKBP3
FUCA1
GIT1
GOLGA2
GPRASP2
H2AC20
H2AX
H2BC21
HAP1
HNRNPC
HNRNPLL
HSF2BP
HSPA14
IDI1
IKZF1
ING5
KAT5
KAT7
KBTBD7
KIFC3
KRT40
LARP7
LDOC1
LGALS8
LRIF1
MACROH2A1
MAGED1
MDC1
MRPS22
MSH2
MSH3
MSH6
MT-ND1
MT2A
MTUS2
NFKB1
NFKBIA
NPC2
PCBP2
PDXK
PDZD8
PIAS1
PIAS4
PIN1
POLR2A
POLR2H
POMZP3
POU2F1
PSMA7
PTN
RABEP1
RAD51
RBBP8
RBMY2BP
RPS20
SELENBP1
SETDB1
SMCHD1
SNRNP200
SNX3
SPAG5
SRC
SRSF2
TCERG1
TERF2
TMEM248
TOP1
TP53
TRAF1
TRAPPC11
TRAPPC8
TULP2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2K
UBE2N
UBE2U
UBE2W
UBE3A
UBR5
UBXN1
WDR61
WRN
XRCC6
ZFP64
ZHX1
ZNF121
ZNF655
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Entrez ID |
1630 |
580 |
HPRD ID |
00391 |
03354 |
Ensembl ID |
ENSG00000187323
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ENSG00000138376
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Uniprot IDs |
P43146
Q49AK4
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A0A087WZ19
A0AVN2
C9IYG1
F6MDI0
F6MDI1
F6MDI2
Q99728
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PDB IDs |
2ED7
2ED8
2ED9
2EDB
2EDD
2EDE
3AU4
4URT
5X83
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1JM7
2NTE
2R1Z
3C5R
3FA2
6M14
7JZV
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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