ZFP1 and MAP3K20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFP1	MAP3K20
Description		ZFP1 zinc finger protein	mitogen-activated protein kinase kinase kinase 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Magnesium Ion Binding RNA Binding MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	DNA Damage Checkpoint Signaling Protein Phosphorylation Cytoskeleton Organization Cell Cycle JNK Cascade Cell Death Cell Differentiation P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Regulation Of Cell Cycle Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint
Pathways		Generic Transcription Pathway
Drugs			Dasatinib Fostamatinib
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Pancreatic cancer ( 25086665)	Haemorrhoidal disease ( 33888516)
Interacting Genes		22 interacting genes: CARD10 CAVIN1 CCDC125 CCDC136 CEP19 CEP70 CIB3 CRLF3 EMD GOLGA6L9 HAP1 HOOK2 KRT40 LDOC1 MAP3K20 MFAP1 MTUS2 POU6F2 TBC1D1 TRIM41 TSPYL2 ZNF250	32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775
Entrez ID		162239	51776
HPRD ID		15724	11791
Ensembl ID		ENSG00000184517	ENSG00000091436
Uniprot IDs		H3BV40 J3KNQ1 Q6P2D0	D4Q8H0 Q9NYL2
PDB IDs			5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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