COX7B and GNMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COX7B	GNMT
Description		cytochrome c oxidase subunit 7B	glycine N-methyltransferase
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respirasome Integral Component Of Membrane Respiratory Chain Complex IV	Cytosol
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding	Protein Binding Folic Acid Binding Glycine Binding Glycine N-methyltransferase Activity Identical Protein Binding S-adenosyl-L-methionine Binding
	Biological Process	Oxidative Phosphorylation Central Nervous System Development Electron Transport Chain Proton Transmembrane Transport	Glycogen Metabolic Process Regulation Of Gluconeogenesis Cellular Protein Modification Process Methionine Metabolic Process One-carbon Metabolic Process Methylation S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Protein Homotetramerization Sarcosine Metabolic Process
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation
Drugs		Cholic Acid N-Formylmethionine	Ademetionine Glycine S-adenosyl-L-homocysteine
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Blood protein levels ( 30072576 29875488) LDL cholesterol levels ( 32203549) Plasma homocysteine levels (post-methionine load test) ( 24651765)
Interacting Genes		1 interacting genes: GNMT	31 interacting genes: ADAMTSL4 ARR3 ARRB1 CCDC153 COX7B CTNS FRG1 GABRQ GAGE2A HDAC7 HPRT1 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NLA NTAQ1 NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP SNRNP200 SRD5A2 STT3B TERF1 TERF2 TERF2IP TINF2 TRIM35 ZNF337
Entrez ID		1349	27232
HPRD ID		04812	05970
Ensembl ID		ENSG00000131174	ENSG00000124713
Uniprot IDs		P24311	A0A0S2Z5F2 Q14749 V9HW60
PDB IDs		5Z62	1R74 2AZT
Enriched GO Terms of Interacting Partners?
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