GNMT and CCDC153

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GNMT	CCDC153
Description		glycine N-methyltransferase	coiled-coil domain containing 153
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding Folic Acid Binding Glycine Binding Glycine N-methyltransferase Activity Identical Protein Binding S-adenosyl-L-methionine Binding	Protein Binding
	Biological Process	Glycogen Metabolic Process Regulation Of Gluconeogenesis Cellular Protein Modification Process Methionine Metabolic Process One-carbon Metabolic Process Methylation S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Protein Homotetramerization Sarcosine Metabolic Process
Pathways		Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation
Drugs		Ademetionine Glycine S-adenosyl-L-homocysteine
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Blood protein levels ( 30072576 29875488) LDL cholesterol levels ( 32203549) Plasma homocysteine levels (post-methionine load test) ( 24651765)	Lymphocyte counts ( 32888494) Plateletcrit ( 27863252)
Interacting Genes		31 interacting genes: ADAMTSL4 ARR3 ARRB1 CCDC153 COX7B CTNS FRG1 GABRQ GAGE2A HDAC7 HPRT1 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NLA NTAQ1 NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP SNRNP200 SRD5A2 STT3B TERF1 TERF2 TERF2IP TINF2 TRIM35 ZNF337	18 interacting genes: AIMP2 BFSP2 C19orf25 CDR2 CDR2L DDIT3 DTNBP1 FAM124B GNMT GORASP2 GUCD1 NECAB2 NUP62 PIN1 POLR2J PSMA1 SPG21 STX5
Entrez ID		27232	283152
HPRD ID		05970	18762
Ensembl ID		ENSG00000124713	ENSG00000248712
Uniprot IDs		A0A0S2Z5F2 Q14749 V9HW60	Q494R4
PDB IDs		1R74 2AZT
Enriched GO Terms of Interacting Partners?
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