POC5 and CETN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid)

		POC5	CETN2
Description		POC5 centriolar protein	centrin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Centriole Cytosol	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding
	Biological Process	Cell Cycle	Mitotic Cell Cycle Nucleotide-excision Repair Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division
Pathways			Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28552196 26961502 28892062 29615537 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Diastolic blood pressure ( 28135244 27841878 30578418) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Metabolic syndrome ( 31589552) Pulse pressure ( 30578418) Total cholesterol levels ( 29615537) Type 2 diabetes ( 30054458 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Weight ( 28552196)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		7 interacting genes: CALM1 CALM2 CALM3 CETN1 CETN2 CETN3 FAM161A	10 interacting genes: ARSA ATP6AP1 CCP110 DDX3X PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC
Entrez ID		134359	1069
HPRD ID		08188	02051
Ensembl ID		ENSG00000152359	ENSG00000147400
Uniprot IDs		Q8NA72	P41208
PDB IDs			1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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