CETN2 and XPC

Number of citations of the paper that reports this interaction (PubMedID 11279143)
103

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		CETN2	XPC
Description		centrin 2	XPC complex subunit, DNA damage recognition and repair factor
Image
GO Annotations	Cellular Component	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium	Nucleotide-excision Repair Complex Nucleotide-excision Repair Factor 2 Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle XPC Complex Site Of DNA Damage
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding	Heteroduplex DNA Loop Binding Bubble DNA Binding Damaged DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Mitotic Cell Cycle Nucleotide-excision Repair Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division	Nucleotide-excision Repair, DNA Damage Recognition Pyrimidine Dimer Repair By Nucleotide-excision Repair DNA Repair Nucleotide-excision Repair Mismatch Repair Response To Xenobiotic Stimulus Response To UV-B Response To Auditory Stimulus Mitotic Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Transcription, DNA-templated UV-damage Excision Repair Regulation Of Mitotic Cell Cycle Phase Transition UV-damage Excision Repair, DNA Incision
Pathways		Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2	SUMOylation of DNA damage response and repair proteins DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: ARSA ATP6AP1 CCP110 DDX3X PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC	16 interacting genes: CETN2 DDB2 ERCC3 GTF2H1 LSM3 MDM2 MRPS25 PSMD4 RAD23A RAD23B RPA1 SMAD1 TDG USP7 XPA ZNF512B
Entrez ID		1069	7508
HPRD ID		02051	02046
Ensembl ID		ENSG00000147400	ENSG00000154767
Uniprot IDs		P41208	Q01831 X5DRB1
PDB IDs		1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH	2A4J 2GGM 2OBH 2RVB
Enriched GO Terms of Interacting Partners?
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