CETN2 and CCP110

Number of citations of the paper that reports this interaction (PubMedID 16760425)
42

Data Source:
HPRD (two hybrid, in vivo)

		CETN2	CCP110
Description		centrin 2	centriolar coiled-coil protein 110
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium	Centrosome Centriole Cytosol Cilium Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Nucleotide-excision Repair Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division	Centriole Replication Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Negative Regulation Of Cilium Assembly Negative Regulation Of Centriole Elongation
Pathways		Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2 RHOV GTPase cycle
Drugs
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		10 interacting genes: ARSA ATP6AP1 CCP110 DDX3X PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC	14 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 ELOB PCNT PNMA1 TFIP11 USP33
Entrez ID		1069	9738
HPRD ID		02051	10848
Ensembl ID		ENSG00000147400	ENSG00000103540
Uniprot IDs		P41208	O43303
PDB IDs		1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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