CETN2 and ATP6AP1

		CETN2	ATP6AP1
Description		centrin 2	ATPase H+ transporting accessory protein 1
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GO Annotations	Cellular Component	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium	Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Proton-transporting Two-sector ATPase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase, V1 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding	Protein Binding ATP Binding Small GTPase Binding
	Biological Process	Mitotic Cell Cycle Nucleotide-excision Repair Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division	Cellular Iron Ion Homeostasis Regulation Of Cellular PH Cellular Response To Increased Oxygen Levels Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Bone Resorption PH Reduction Positive Regulation Of Exocytosis Establishment Of Organelle Localization Positive Regulation Of ERK1 And ERK2 Cascade Proton Transmembrane Transport Positive Regulation Of Osteoclast Development
Pathways		Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2	Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		10 interacting genes: ARSA ATP6AP1 CCP110 DDX3X PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC	11 interacting genes: ABCD1 ANG CETN2 CTAG1B ERBB2 HBA1 LARP1 NR1I2 NT5E OGT RHOU
Entrez ID		1069	537
HPRD ID		02051	02184
Ensembl ID		ENSG00000147400	ENSG00000071553
Uniprot IDs		P41208	A0A0C4DGX8 A0A384MQW4 Q15904
PDB IDs		1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH	6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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