FLACC1 and TXNDC5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FLACC1	TXNDC5
Description		flagellum associated containing coiled-coil domains 1	thioredoxin domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Outer Dense Fiber Cellular_component Cytoplasm Cytoplasmic Vesicle Sperm Fibrous Sheath Sperm Flagellum	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process		Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance
Pathways			Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)
Interacting Genes		23 interacting genes: ATP6V1H BLK CRK DISC1 DVL3 FAM90A1 ICA1L INO80B LGALS14 LONRF1 PRPF31 SPG21 SSX2 SSX2B SSX4 SSX4B STK16 SULT2B1 TCL1A TEPSIN TRIM41 TXNDC5 YES1	28 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA OGT PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2
Entrez ID		130540	81567
HPRD ID		12444	18249
Ensembl ID		ENSG00000155749	ENSG00000239264
Uniprot IDs		A8K8B8 Q96Q35	A0A024QZV0 Q8NBS9
PDB IDs			2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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