TXNDC5 and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 21516116)
114

Data Source:
BioGRID (two hybrid)

		TXNDC5	RAB3IP
Description		thioredoxin domain containing 5	RAB3A interacting protein
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Nucleus Microtubule Organizing Center Cytosol Lamellipodium Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		28 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA OGT PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2	33 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A GPD2 KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		81567	117177
HPRD ID		18249	10565
Ensembl ID		ENSG00000239264	ENSG00000127328
Uniprot IDs		A0A024QZV0 Q8NBS9	Q96QF0
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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