FLACC1 and ATP6V1H

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FLACC1	ATP6V1H
Description		flagellum associated containing coiled-coil domains 1	ATPase H+ transporting V1 subunit H
Image		No pdb structure
GO Annotations	Cellular Component	Outer Dense Fiber Cellular_component Cytoplasm Cytoplasmic Vesicle Sperm Fibrous Sheath Sperm Flagellum	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding ATP Hydrolysis Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process		Endocytosis Vacuolar Acidification Regulation Of Macroautophagy Regulation Of Catalytic Activity Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		23 interacting genes: ATP6V1H BLK CRK DISC1 DVL3 FAM90A1 ICA1L INO80B LGALS14 LONRF1 PRPF31 SPG21 SSX2 SSX2B SSX4 SSX4B STK16 SULT2B1 TCL1A TEPSIN TRIM41 TXNDC5 YES1	10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14
Entrez ID		130540	51606
HPRD ID		12444	10591
Ensembl ID		ENSG00000155749	ENSG00000047249
Uniprot IDs		A8K8B8 Q96Q35	A0A024R7U9 A0A024R7X3 B3KUZ7 Q9UI12
PDB IDs			6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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