ATP6V1H and SNPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V1H	SNPH
Description		ATPase H+ transporting V1 subunit H	syntaphilin
Image			No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Exosome	Cytoplasm Mitochondrion Cytoplasmic Microtubule Integral Component Of Membrane Mitochondrial Membrane Presynaptic Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding ATP Hydrolysis Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding Syntaxin-1 Binding
	Biological Process	Endocytosis Vacuolar Acidification Regulation Of Macroautophagy Regulation Of Catalytic Activity Proton Transmembrane Transport	Neurotransmitter Secretion Brain Development Synaptic Vesicle Docking Neuron Differentiation
Pathways		ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Body mass index ( 28552196) Lean body mass ( 28552196) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14	6 interacting genes: ATP6V1H PRKACA RHBDD2 STUB1 STX1A XPA
Entrez ID		51606	9751
HPRD ID		10591	16081
Ensembl ID		ENSG00000047249	ENSG00000101298
Uniprot IDs		A0A024R7U9 A0A024R7X3 B3KUZ7 Q9UI12	A0A3B3IRY9 O15079
PDB IDs		6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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