PIGU and GPAA1

Number of citations of the paper that reports this interaction (PubMedID 22939629)
326

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		PIGU	GPAA1
Description		phosphatidylinositol glycan anchor biosynthesis class U	glycosylphosphatidylinositol anchor attachment 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane GPI-anchor Transamidase Complex	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex
	Molecular Function	Protein Binding GPI Anchor Binding	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding
	Biological Process	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Protein Localization To Cell Surface Regulation Of Receptor Signaling Pathway Via JAK-STAT	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly
Pathways		Attachment of GPI anchor to uPAR	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Brown vs. black hair color ( 30531825) Colorectal cancer or advanced adenoma ( 30510241) Cutaneous melanoma or hair colour ( 32341527) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Melanoma ( 28212542) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Smoking status (ever vs never smokers) ( 30643258) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Weight ( 28552196)	Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: F2RL1 GPAA1 KASH5	19 interacting genes: ADAMDEC1 AGTR1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GNRHR GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL
Entrez ID		128869	8733
HPRD ID		12250	04334
Ensembl ID		ENSG00000101464	ENSG00000197858
Uniprot IDs		Q9H490	O43292
PDB IDs
Enriched GO Terms of Interacting Partners?
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