SP7 and FAM124B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SP7	FAM124B
Description		Sp7 transcription factor	family with sequence similarity 124 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleoplasm Mitochondrion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding DEAD/H-box RNA Helicase Binding Metal Ion Binding	Protein Binding
	Biological Process	Osteoblast Differentiation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Positive Regulation Of Stem Cell Differentiation
Pathways		RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Bone mineral density (spine) ( 19079262 19801982) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 31562340) Hypospadias (moderate to severe) ( 31856834) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lumbar spine bone mineral density ( 22504420) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Serum alkaline phosphatase levels ( 33547301) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)
Interacting Genes		9 interacting genes: CBL CBLB FAM124B FBXW7 GAS8 KRT72 MAPK14 QARS1 TRIM62	68 interacting genes: ABI1 ABI3 ADAMTSL4 BHLHB9 BIRC7 BLZF1 CARD9 CCDC153 CCDC85B CUL3 CYSRT1 EFEMP2 EFHC2 ESM1 GIGYF1 GKAP1 GOLGA2 GPRASP2 GRB7 HSF2BP IHO1 IKZF3 ISCA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP9-3 LHX3 LZTS2 MBD3L1 MDFI MIPOL1 MKRN3 MTUS2 MYF5 NADK NOTCH2NLA RBPMS RINT1 RSPH3 SEPTIN14 SH2B2 SP7 SSX2IP TCF4 TLE5 TRAF2 TRIM37 TRIM42 TRIM54 TRIM8 TRIM9 TRIP6 USHBP1 USP54 WDR83 ZBED1 ZNF69 ZNF774 ZRANB1
Entrez ID		121340	79843
HPRD ID		05971	08663
Ensembl ID		ENSG00000170374	ENSG00000124019
Uniprot IDs		A0A024RAY8 Q8TDD2	Q9H5Z6
PDB IDs
Enriched GO Terms of Interacting Partners?
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