FAM124B and BIRC7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FAM124B	BIRC7
Description		family with sequence similarity 124 member B	baculoviral IAP repeat containing 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Lens Development In Camera-type Eye Apoptotic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)
Interacting Genes		68 interacting genes: ABI1 ABI3 ADAMTSL4 BHLHB9 BIRC7 BLZF1 CARD9 CCDC153 CCDC85B CUL3 CYSRT1 EFEMP2 EFHC2 ESM1 GIGYF1 GKAP1 GOLGA2 GPRASP2 GRB7 HSF2BP IHO1 IKZF3 ISCA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP9-3 LHX3 LZTS2 MBD3L1 MDFI MIPOL1 MKRN3 MTUS2 MYF5 NADK NOTCH2NLA RBPMS RINT1 RSPH3 SEPTIN14 SH2B2 SP7 SSX2IP TCF4 TLE5 TRAF2 TRIM37 TRIM42 TRIM54 TRIM8 TRIM9 TRIP6 USHBP1 USP54 WDR83 ZBED1 ZNF69 ZNF774 ZRANB1	37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1
Entrez ID		79843	79444
HPRD ID		08663	05761
Ensembl ID		ENSG00000124019	ENSG00000101197
Uniprot IDs		Q9H5Z6	Q96CA5
PDB IDs			1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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