CMTM5 and SUCLA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		CMTM5	SUCLA2
Description		CKLF like MARVEL transmembrane domain containing 5	succinate-CoA ligase ADP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Succinyl-CoA Pathway
Pathways			Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS			Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Serum metabolite levels ( 33031748) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		131 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35C2 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	11 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B FKBP7 MAGEA11 MAL2 MTNR1A SEC23A TNFRSF10D
Entrez ID		116173	8803
HPRD ID		06986	06798
Ensembl ID		ENSG00000166091	ENSG00000136143
Uniprot IDs		Q96DZ9	E5KS60 Q9P2R7 Q9Y4T0
PDB IDs			6G4Q
Enriched GO Terms of Interacting Partners?
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