CLCN1 and FKBP8

Number of citations of the paper that reports this interaction (PubMedID 27580824)
9

Data Source:
BioGRID (pull down, affinity chromatography technology)

		CLCN1	FKBP8
Description		chloride voltage-gated channel 1	FKBP prolyl isomerase 8
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding
	Biological Process	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Regulation Of Gene Expression Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process
Pathways		Stimuli-sensing channels	Ub-specific processing proteases
Drugs
Diseases
GWAS			Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		7 interacting genes: AHSA1 APPBP2 CIDEB FAM9B FKBP8 PRDM5 STIP1	50 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR OGT PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SHANK3 SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1
Entrez ID		1180	23770
HPRD ID		00320	05327
Ensembl ID		ENSG00000188037	ENSG00000105701
Uniprot IDs		P35523	A0A024R7P2 B2R8G6 Q14318
PDB IDs		6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU	2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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