DSTN and CFL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		DSTN	CFL2
Description		destrin, actin depolymerizing factor	cofilin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding Actin Filament Binding
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Cell Motility Actin Filament Severing	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing
Pathways
Drugs		Dodecyldimethylamine N-oxide
Diseases
GWAS		Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Takayasu arteritis ( 33308445)
Interacting Genes		8 interacting genes: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2	15 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LAIR1 LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I ZYG11B
Entrez ID		11034	1073
HPRD ID		16446	03262
Ensembl ID		ENSG00000125868	ENSG00000165410
Uniprot IDs		P60981 V9HWA6	Q549N0 Q9Y281
PDB IDs
Enriched GO Terms of Interacting Partners?
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