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DGAT1

Description diacylglycerol O-acyltransferase 1
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Integral Component Of Membrane
  • Specific Granule Membrane
Molecular Function
  • 2-acylglycerol O-acyltransferase Activity
  • Diacylglycerol O-acyltransferase Activity
  • Protein Binding
  • O-acyltransferase Activity
  • Acyltransferase Activity
  • Identical Protein Binding
  • Retinol O-fatty-acyltransferase Activity
Biological Process
  • Monoacylglycerol Biosynthetic Process
  • Triglyceride Metabolic Process
  • Triglyceride Biosynthetic Process
  • Lipid Storage
  • Very-low-density Lipoprotein Particle Assembly
  • Long-chain Fatty-acyl-CoA Metabolic Process
  • Retinol Metabolic Process
  • Diacylglycerol Metabolic Process
  • Fatty Acid Homeostasis
Pathways
  • Acyl chain remodeling of DAG and TAG
  • Neutrophil degranulation
  • Triglyceride biosynthesis
Drugs
Diseases
GWAS
  • Dupuytren's disease ( 28886342)
  • Fasting glucose ( 34059833)
Interacting Genes 4 interacting genes: CCR9 CD1A GABRA4 GPAA1
Entrez ID 8694
HPRD ID 05360
Ensembl ID ENSG00000185000
Uniprot IDs O75907
PDB IDs 6VP0 6VYI 6VZ1
Enriched GO Terms of Interacting Partners?
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