CAP2 and CFL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CAP2	CFL2
Description		cyclase associated actin cytoskeleton regulatory protein 2	cofilin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Adenylate Cyclase Binding Identical Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	Cell Morphogenesis Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity CAMP-mediated Signaling Regulation Of Adenylate Cyclase Activity	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing
Pathways		Role of ABL in ROBO-SLIT signaling
Drugs
Diseases
GWAS		Haemorrhoidal disease ( 33888516) Height ( 18391951) Mitochondrial DNA levels ( 25240745) QT interval ( 29213071) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Takayasu arteritis ( 33308445)
Interacting Genes		10 interacting genes: ACTG1 ADO ALAS1 CAP1 CFL2 DTNBP1 GRXCR1 MT1P3 PRPF40A YWHAE	15 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LAIR1 LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I ZYG11B
Entrez ID		10486	1073
HPRD ID		10808	03262
Ensembl ID		ENSG00000112186	ENSG00000165410
Uniprot IDs		P40123 Q5JPJ8	Q549N0 Q9Y281
PDB IDs
Enriched GO Terms of Interacting Partners?
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