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ATP6AP1

Description ATPase H+ transporting accessory protein 1
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Endosome Membrane
  • Integral Component Of Membrane
  • Proton-transporting Two-sector ATPase Complex
  • Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
  • Proton-transporting V-type ATPase, V1 Domain
  • Plasma Membrane Proton-transporting V-type ATPase Complex
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • ATP Binding
  • Small GTPase Binding
Biological Process
  • Cellular Iron Ion Homeostasis
  • Regulation Of Cellular PH
  • Cellular Response To Increased Oxygen Levels
  • Positive Regulation Of Osteoblast Differentiation
  • Positive Regulation Of Bone Resorption
  • PH Reduction
  • Positive Regulation Of Exocytosis
  • Establishment Of Organelle Localization
  • Positive Regulation Of ERK1 And ERK2 Cascade
  • Proton Transmembrane Transport
  • Positive Regulation Of Osteoclast Development
Pathways
  • Insulin receptor recycling
  • RHOA GTPase cycle
  • Transferrin endocytosis and recycling
  • Ion channel transport
Drugs
  • Tiludronic acid
Diseases
GWAS
Interacting Genes 11 interacting genes: ABCD1 ANG CETN2 CTAG1B ERBB2 HBA1 LARP1 NR1I2 NT5E OGT RHOU
Entrez ID 537
HPRD ID 02184
Ensembl ID ENSG00000071553
Uniprot IDs A0A0C4DGX8 A0A384MQW4 Q15904
PDB IDs 6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025