FARS2 and KCTD17

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FARS2	KCTD17
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	potassium channel tetramerization domain containing 17
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Cytoplasm Endoplasmic Reticulum Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Cell Projection Organization Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cilium Assembly Protein Homooligomerization
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)	Hemoglobin levels ( 33491795) Iron status biomarkers (ferritin levels) ( 28334935) Liver iron content ( 34128465) Mean corpuscular hemoglobin concentration ( 28453575) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Red blood cell traits ( 23222517)
Interacting Genes		69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1	28 interacting genes: AQP1 ARL8A CRK CUL3 DMC1 EGR2 FARS2 LAT LNX1 LRRC18 MGAT5B NCK2 NIF3L1 NUDT18 OR51E1 PLCG2 PSMA1 RBX1 RIN3 RWDD4 SPHK1 SPRR2F STK16 SUV39H2 TCHP TINF2 TUBGCP4 UBE2D1
Entrez ID		10667	79734
HPRD ID		09946	07764
Ensembl ID		ENSG00000145982	ENSG00000100379
Uniprot IDs		O95363	A0A087WX35 Q8N5Z5
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW	5A6R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?