FARS2 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FARS2	FKBP7
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	FKBP prolyl isomerase 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Protein Peptidyl-prolyl Isomerization Peptidyl-proline Modification
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1	81 interacting genes: ABHD16A ADIPOQ AGPS AP1M1 APOD ASPH BMP10 BRICD5 CDIPT CERCAM CIAO2A CLCA4 CLDN19 CTSA CXCL16 DIABLO FAM3C FARS2 GET3 H4C7 HHATL HSBP1L1 IER3 IFITM3 IRF2 JOSD2 LAT MAN2B2 MIEF2 MRM1 NFU1 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PDE11A PEX19 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RBM45 RPRM RUSF1 SGTA SLC38A7 SLC7A14 SNX1 SNX12 STX7 STX8 SUCLA2 TARS2 TCP11X2 THAP4 THSD7B TMEM108 TMEM120B TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TTC30A TTC30B TTPA TXNDC12 UBIAD1 UBQLN4 UPK1B VSTM4 WFDC2 WIPI2 YIPF6 ZFPL1
Entrez ID		10667	51661
HPRD ID		09946	08451
Ensembl ID		ENSG00000145982	ENSG00000079150
Uniprot IDs		O95363	Q9Y680
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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