FARS2 and ZNF526

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FARS2	ZNF526
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	zinc finger protein 526
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Regulation Of Transcription By RNA Polymerase II
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)	Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)
Interacting Genes		69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1	54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837
Entrez ID		10667	116115
HPRD ID		09946	15818
Ensembl ID		ENSG00000145982	ENSG00000167625
Uniprot IDs		O95363	H9ZYJ3 Q8TF50
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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