FARS2 and HIGD1C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FARS2	HIGD1C
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	HIG1 hypoxia inducible domain family member 1C
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Mitochondrion Integral Component Of Membrane
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Mitochondrial Respirasome Assembly
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
Interacting Genes		69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1	13 interacting genes: APOC1 CIDEB CYB5R1 FARS2 GAD2 MTERF3 NTAQ1 PBX3 RBFA SYT16 TCEA2 TMEM14B TMEM31
Entrez ID		10667	613227
HPRD ID		09946	19625
Ensembl ID		ENSG00000145982	ENSG00000214511
Uniprot IDs		O95363	A8MV81
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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