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SMPD2

Description sphingomyelin phosphodiesterase 2
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Caveola
  • Membrane
  • Cell Periphery
Molecular Function
  • Phospholipase Activity
  • Sphingomyelin Phosphodiesterase Activity
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Sphingomyelin Metabolic Process
  • Sphingomyelin Catabolic Process
  • Response To Mechanical Stimulus
  • Sphingolipid Catabolic Process
  • Intracellular Signal Transduction
  • Ceramide Biosynthetic Process
Pathways
  • Glycosphingolipid metabolism
  • Ceramide signalling
  • TNFR1-mediated ceramide production
Drugs
Diseases
GWAS
  • Height ( 18391951)
Interacting Genes 15 interacting genes: ARFIP1 CCN1 COQ8A GAD2 NDRG4 PBX3 PGRMC2 PIK3CG PITPNC1 SLC10A1 SLC7A8 STAR TMEM14B TMEM167B TMEM31
Entrez ID 6610
HPRD ID 04608
Ensembl ID ENSG00000135587
Uniprot IDs O60906
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025