LEO1

Description		LEO1 homolog, Paf1/RNA polymerase II complex component
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Centrosome Cdc73/Paf1 Complex
	Molecular Function	Protein Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding
	Biological Process	Endodermal Cell Fate Commitment Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Population Maintenance Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation
Pathways		Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Frailty index ( 34431594)
Interacting Genes		8 interacting genes: BHLHB9 CSNK2A1 CTNNB1 ERCC6 H1-2 POLR2A TCEA1 TCEA3
Entrez ID		123169
HPRD ID		11231
Ensembl ID		ENSG00000166477
Uniprot IDs		Q8WVC0
PDB IDs		4M6T 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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